Plasdone
Plasdone povidones are a family of water-soluble polymers based on N-vinylpyrrolidone that combine a unique set of properties for application in a wide variety of dosage forms. Plasdone povidones are commonly used as binders for the development of tablet formulations, whether manufactured by wet granulation, dry granulation, or direct compression.
| Grade | Average Molecular Weight | K-value Viscosity | Application |
|---|---|---|---|
|
K-12 |
4,000 |
10.2 - 13.8 |
Drug solubilization, viscosifier, suspending agent, crystallization inhibitor. |
|
K-17 |
10,000 |
16.0 - 17.5 |
Drug solubilization, crystallization inhibitor. |
|
K-25 |
34,000 |
24 - 26 |
Tablet binding, film coating, drug solubilization, viscosifier. |
|
K-29/32 |
58,000 |
29 - 32 |
Tablet binding, film coating, viscosifier, film former, rheology modifier. |
|
K-90 |
1,300,000 |
85 - 95 |
Tablet binding, modified release, viscosifier, tissue engineering scaffolds. |
|
C-12 |
4,000 |
10.2 - 13.8 |
Drug solubilization, viscosifier, suspending agent, crystallization inhibitor, lyophilization, bioavailability. |
|
C-15 |
9,400 |
15.5 - 17.5 |
Drug solubilization, viscosifier, suspending agent crystallization inhibitor, bioavailability. |
|
C-17 |
10,000 |
16.0 - 17.5 |
Drug solubilization, viscosifier, suspending agent crystallization inhibitor, bioavailability. |
|
C-30 |
58,000 |
29.0 - 32.0 |
Tablet binding, film coating, viscosifier, film former, rheology modifier. |
* C grades have low pyrogen levels.
