F-Melt

F-MELT is a proprietary co-spray dried excipient launched by Fuji Chemical Industries Co. Ltd., Japan in 2005. F-MELT is designed not only for manufacturing orally disintegrating tablets (ODTs) and tablets that dissolve fast in the oral cavity without the need for water but is also an excellent excipient for soft chewable tablets. It is suitable for manufacturing directly compressible ODT simply by blending it with active pharmaceutical ingredients (APIs) and lubricants.

 

Grades Generic Name Mean Particle Size Application
F-Melt Type C
D-Mannitol, Xylitol, MCC, Crospovidone, Fujicalin.
121
Ready to use directly Compressible with API for ODT and chewable Tablets. Orally disintegration time is less than 30 seconds. Pleasant mouth feel, and tablet hardness can be achieved more than 50N.
F-Melt Type M
D-Mannitol, Xylitol, MCC, Crospovidone, Neusilin.
112
Ready to use directly Compressible with API for ODT and chewable Tablets. Orally disintegration time is less than 30 seconds. Pleasant mouth feel, and tablet hardness can be achieved more than 50N.
F-Melt F1
Waxy rice starch, MCC, Fujicalin.
139
Ready to use directly Compressible with API for ODT and chewable Tablets. Orally disintegration time is less than 30 seconds. Pleasant mouth feel, and tablet hardness can be achieved more than 50N.